ABSTRACT
Pancreatectomy is difficult and has various complications. Pancreatic fistula is one of the most serious postoperative complications after pancreatectomy. It will corrode the surrounding tissues of pancreas, which will cause abdominal infection, if the drainage of pancreatic fistula is not complete. Pancreatic fistula combined with abdominal infection may lead to systemic inflammatory response syndrome. Patients at the severe stage often die of multiple organ dysfunction and septic shock. Up to now, the treatment of pancreatic fistula with abdominal infection has not been well determined. This paper reviewed the relevant studies of pancreatic fistula combined with abdominal infection, analyzed the diagnostic criteria and common pathogenic bacteria of pancreatic fistula with abdominal infection, discussed the indications and systematic treatment plan of the surgical intervention, in order to provide direction for the treatment of pancreatic fistula combined with abdominal infection.
ABSTRACT
Cardiovascular disease is still the world's first cause of death,its morbidity and mortality rates are still increasing. Recent studies have shown that circular RNA is involved in the regulation of gene expression and plays a significant role in the pathogenesis of cardiovascular diseases. Circular RNA is a kind of special non-coding RNA, which can regulate the expression of genes at the level of post-transcription or transcription,then regulate various life activities as well as cardiovascular system diseases,becoming a latest research hot spot in the field of RNA. Nowadays,more and more attention is paid to the role of cyclic RNA in the development, early diagnosis, disease monitoring and other aspects of cardiovascular diseases. In this paper,we make an overview of the latest research on circRNAs from the aspects of genesis, function,and the relationship with cardiovas cular diseases,and so on.